AirHint found the following cheapest return flights from Santiago (SCL) to Lisbon (LIS) in September 2025 (see full year).

Return flights

28 Sep - 09 Oct	LATAM Airlines Group
06 Sep - 14 Sep	LATAM Airlines Group
15 Sep - 28 Sep	LATAM Airlines Group
21 Sep - 28 Sep	JetSmart
29 Sep - 09 Oct	LATAM Airlines Group
15 Sep - 25 Sep	JetSmart
14 Sep - 28 Sep	Turkish Airlines
03 Sep - 24 Sep	LATAM Airlines Group
19 Sep - 25 Sep	LATAM Airlines Group
16 Sep - 23 Sep	LATAM Airlines Group
20 Sep - 01 Oct	Avianca
01 Sep - 23 Oct	LATAM Airlines Group
16 Sep - 27 Sep	LATAM Airlines Group
06 Sep - 20 Sep	LATAM Airlines Group
13 Sep - 12 Oct	Avianca
11 Sep - 18 Oct	Avianca

Also check the deals for one-way flights from Santiago to Lisbon in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Lisbon

Cheap car rent in Lisbon

Cheapest return flights from Santiago to Lisbon in September from 811€

Return flights