AirHint found the following cheapest return flights from Santiago (SCL) to Lisbon (LIS) in October 2025 (see full year).

Return flights

17 Oct - 19 Nov	British Airways
20 Oct - 10 Nov	LATAM Airlines Group
06 Oct - 23 Oct	LATAM Airlines Group
26 Oct - 31 Oct	Sky Airline
14 Oct - 23 Oct	Avianca
11 Oct - 28 Oct	LATAM Airlines Group
11 Oct - 25 Oct	Avianca
01 Oct - 02 Nov	Copa
04 Oct - 08 Oct	LATAM Airlines Group
05 Oct - 29 Oct	LATAM Airlines Group
02 Oct - 11 Oct	LATAM Airlines Group
11 Oct - 30 Oct	Avianca

Also check the deals for one-way flights from Santiago to Lisbon in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Lisbon in October from 699€

Return flights