Cheapest return flights from Santiago to Guayaquil in September from 341€

AirHint found the following cheapest return flights from Santiago (SCL) to Guayaquil (GYE) in September 2025 (see full year).

Return flights

21 Sep - 30 Sep LATAM Airlines Group
27 Sep - 15 Oct Copa
27 Sep - 01 Oct Copa
08 Sep - 14 Sep Avianca
23 Sep - 15 Oct Avianca
18 Sep - 25 Sep LATAM Airlines Group
08 Sep - 15 Sep LATAM Airlines Group
08 Sep - 15 Sep LATAM Airlines Group direct
08 Sep - 14 Sep LATAM Airlines Group direct
08 Sep - 21 Sep Avianca
18 Sep - 21 Sep LATAM Airlines Group
08 Sep - 20 Sep Avianca
12 Sep - 15 Sep JetSmart

Also check the deals for one-way flights from Santiago to Guayaquil in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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