AirHint found the following cheapest return flights from Rome (ROM) to Sao Paulo (GRU) in April 2026 (see full year).

Return flights

11 Apr - 25 Apr	Iberia
14 Apr - 20 May	SWISS
06 Apr - 26 Apr	Royal Air Maroc
15 Apr - 29 Apr	Royal Air Maroc
08 Apr - 22 Apr	SWISS
09 Apr - 22 Apr	SWISS
07 Apr - 22 Apr	SWISS
08 Apr - 23 Apr	Air Europa
28 Apr - 03 May	Air Europa
13 Apr - 24 Apr	Air Europa
06 Apr - 19 Apr	Royal Air Maroc
28 Apr - 26 May	Iberia
09 Apr - 25 Apr	Wizz Air Malta
22 Apr - 16 May	Air Europa
22 Apr - 13 May	Air Europa
10 Apr - 10 May	Air Europa
29 Apr - 06 May	Air Europa
24 Apr - 03 May	LATAM Airlines Group
27 Apr - 23 May	TAP
27 Apr - 25 May	Delta

Also check the deals for one-way flights from Rome to Sao Paulo in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Sao Paulo in April from 642€

Return flights