AirHint found the following cheapest return flights from Rome (ROM) to Sao Paulo (GRU) in April 2026 (see full year).

Return flights

12 Apr - 21 Apr	Air Europa
07 Apr - 16 Apr	Air Europa
20 Apr - 11 May	Air Canada
20 Apr - 04 May	Air Canada
08 Apr - 24 Apr	Air Europa
23 Apr - 05 May	Air Europa
13 Apr - 24 Apr	Air Europa
09 Apr - 22 Apr	Air Europa
15 Apr - 25 Apr	Iberia
04 Apr - 12 Apr	Delta
05 Apr - 20 Apr	Delta
21 Apr - 28 Apr	Delta
02 Apr - 11 Apr	Delta
03 Apr - 11 May	Delta
24 Apr - 08 May	Air Europa
29 Apr - 03 May	Air Europa
30 Apr - 09 May	Air Europa
20 Apr - 04 May	ITA Airways	direct
20 Apr - 11 May	ITA Airways	direct
23 Apr - 05 May	ITA Airways	direct

Also check the deals for one-way flights from Rome to Sao Paulo in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Sao Paulo in April from 660€

Return flights