AirHint found the following cheapest return flights from Rome (ROM) to Cape Town (CPT) in September 2025 (see full year).

Return flights

11 Sep - 24 Sep	KLM
09 Sep - 16 Sep	KLM
25 Sep - 30 Oct	Ethiopian Airlines
20 Sep - 30 Sep	Condor
23 Sep - 01 Oct	Condor
26 Sep - 25 Oct	Ethiopian Airlines
17 Sep - 28 Sep	KLM
12 Sep - 21 Sep	KLM
08 Sep - 18 Sep	Air France
25 Sep - 25 Oct	Ethiopian Airlines
25 Sep - 30 Sep	Condor
25 Sep - 31 Oct	KLM
25 Sep - 01 Oct	Condor
28 Sep - 04 Oct	Ethiopian Airlines
28 Sep - 30 Sep	EgyptAir
06 Sep - 10 Sep	KLM
27 Sep - 30 Sep	Condor
27 Sep - 01 Oct	Condor
29 Sep - 04 Oct	Ethiopian Airlines
27 Sep - 04 Oct	Wizz Air

Also check the deals for one-way flights from Rome to Cape Town in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Cape Town in September from 574€

Return flights