Cheapest return flights from Panama City to Santiago in October from 542€

Best time to book flights for Panama City (PTY) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest return flights from Panama City (PTY) to Santiago (SCL) in October 2025 (see full year).

Return flights

08 Oct - 26 Oct Avianca
08 Oct - 26 Oct Copa direct

Also check the deals for one-way flights from Panama City to Santiago in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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