AirHint found the following cheapest return flights from Panama City (PTY) to Santiago (SCL) in January 2026 (see full year).

Return flights

23 Jan - 23 Feb	Avianca
31 Jan - 07 Feb	Avianca
21 Jan - 28 Jan	Avianca
22 Jan - 29 Jan	Avianca
23 Jan - 30 Jan	Avianca
29 Jan - 31 Jan	Avianca
27 Jan - 31 Jan	Avianca
23 Jan - 23 Feb	Copa	direct
31 Jan - 07 Feb	Copa	direct
23 Jan - 30 Jan	Copa	direct
20 Jan - 12 Feb	Copa	direct
22 Jan - 29 Jan	Copa	direct
21 Jan - 28 Jan	Copa	direct
29 Jan - 31 Jan	Copa	direct
27 Jan - 31 Jan	Copa	direct

Also check the deals for one-way flights from Panama City to Santiago in January.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Panama City to Santiago in January from 482€

Return flights