AirHint found the following cheapest return flights from Panama City (PTY) to Guatemala City (GUA) in November 2025 (see full year).

Return flights

22 Nov - 29 Nov	Avianca
23 Nov - 07 Dec	Avianca
23 Nov - 08 Dec	Avianca
23 Nov - 09 Dec	Avianca
08 Nov - 22 Nov	Avianca
16 Nov - 27 Nov	Avianca
22 Nov - 14 Dec	Avianca
24 Nov - 06 Dec	Avianca
23 Nov - 06 Dec	Avianca
02 Nov - 06 Nov	Avianca
14 Nov - 17 Nov	Avianca
20 Nov - 24 Nov	Avianca
01 Nov - 10 Nov	Avianca
01 Nov - 03 Nov	Avianca
01 Nov - 06 Nov	Avianca
01 Nov - 05 Nov	Avianca
28 Nov - 23 Dec	Avianca
23 Nov - 09 Dec	Copa	direct
27 Nov - 11 Dec	Copa
23 Nov - 06 Dec	Copa	direct

Also check the deals for one-way flights from Panama City to Guatemala City in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Panama City to Guatemala City in November from 202€

Return flights