AirHint found the following cheapest return flights from Prague (PRG) to Lisbon (LIS) in September 2025 (see full year).

Return flights

30 Sep - 08 Oct	easyJet
30 Sep - 09 Oct	easyJet
30 Sep - 07 Oct	easyJet
29 Sep - 08 Oct	easyJet
23 Sep - 01 Oct	Ryanair
22 Sep - 06 Oct	Volotea
23 Sep - 06 Oct	Ryanair
27 Sep - 30 Sep	Ryanair
17 Sep - 29 Sep	Volotea
10 Sep - 21 Oct	easyJet
27 Sep - 02 Oct	Wizz Air UK
27 Sep - 03 Oct	Wizz Air UK
23 Sep - 29 Sep	Ryanair
27 Sep - 29 Sep	Ryanair
16 Sep - 22 Sep	Ryanair
23 Sep - 30 Sep	Ryanair
15 Sep - 24 Sep	Volotea
17 Sep - 22 Sep	Volotea
20 Sep - 24 Sep	Ryanair
29 Sep - 30 Sep	Ryanair

Also check the deals for one-way flights from Prague to Lisbon in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Prague to Lisbon in September from 114€

Return flights