AirHint found the following cheapest return flights from Prague (PRG) to Lisbon (LIS) in October 2025 (see full year).

Return flights

29 Oct - 05 Nov	Eurowings
30 Oct - 08 Nov	easyJet
31 Oct - 08 Nov	Ryanair
28 Oct - 08 Nov	easyJet
28 Oct - 13 Nov	easyJet
30 Oct - 10 Nov	easyJet
30 Oct - 05 Nov	easyJet
28 Oct - 07 Nov	Lufthansa
29 Oct - 07 Nov	Lufthansa
31 Oct - 10 Nov	Ryanair
21 Oct - 24 Oct	TAP	direct
28 Oct - 30 Oct	easyJet
28 Oct - 31 Oct	easyJet
27 Oct - 29 Oct	Ryanair
27 Oct - 28 Oct	Condor
28 Oct - 29 Oct	easyJet
21 Oct - 30 Oct	Smart Wings
21 Oct - 31 Oct	Smart Wings
22 Oct - 30 Oct	Volotea
22 Oct - 24 Oct	easyJet

Also check the deals for one-way flights from Prague to Lisbon in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Prague to Lisbon in October from 157€

Return flights