AirHint found the following cheapest return flights from Palermo (PMO) to Prague (PRG) in December 2025 (see full year).

Return flights

02 Dec - 06 Dec	easyJet
02 Dec - 04 Dec	easyJet
01 Dec - 04 Dec	easyJet
01 Dec - 03 Dec	easyJet
07 Dec - 11 Dec	Ryanair
07 Dec - 12 Dec	Ryanair
13 Dec - 15 Dec	easyJet
08 Dec - 12 Dec	Ryanair
11 Dec - 15 Dec	easyJet
04 Dec - 12 Dec	easyJet
27 Dec - 01 Jan	Ryanair
22 Dec - 10 Jan	Ryanair
26 Dec - 01 Jan	easyJet
30 Dec - 01 Jan	Aeroitalia
31 Dec - 03 Jan	easyJet
31 Dec - 02 Jan	easyJet
27 Dec - 02 Jan	Ryanair
31 Dec - 04 Jan	easyJet
28 Dec - 02 Jan	Lufthansa
31 Dec - 05 Jan	Ryanair

Also check the deals for one-way flights from Palermo to Prague in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Palermo to Prague in December from 111€

Return flights