AirHint found the following cheapest return flights from Palermo (PMO) to Prague (PRG) in December 2025 (see full year).

Return flights

11 Dec - 15 Dec	easyJet
02 Dec - 06 Dec	easyJet
13 Dec - 15 Dec	easyJet
09 Dec - 13 Dec	easyJet
01 Dec - 31 Dec	Ryanair
10 Dec - 14 Dec	easyJet
12 Dec - 16 Dec	easyJet
12 Dec - 15 Dec	easyJet
02 Dec - 04 Dec	easyJet
16 Dec - 20 Dec	Ryanair
31 Dec - 03 Jan	easyJet
27 Dec - 03 Jan	Ryanair
30 Dec - 05 Jan	Ryanair
29 Dec - 03 Jan	easyJet
28 Dec - 03 Jan	easyJet
29 Dec - 04 Jan	easyJet
28 Dec - 02 Jan	easyJet

Also check the deals for one-way flights from Palermo to Prague in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Palermo to Prague in December from 137€

Return flights