AirHint found the following cheapest return flights from Palermo (PMO) to Istanbul (IST) in November 2025 (see full year).

Return flights

06 Nov - 09 Nov	Aeroitalia
09 Nov - 12 Nov	easyJet
26 Nov - 30 Nov	Aeroitalia
10 Nov - 17 Nov	Ryanair
10 Nov - 14 Nov	Ryanair
24 Nov - 30 Nov	Ryanair
12 Nov - 17 Nov	Aeroitalia
14 Nov - 20 Nov	Aeroitalia
28 Nov - 30 Nov	Ryanair
27 Nov - 30 Nov	Aeroitalia
28 Nov - 07 Dec	Aeroitalia
26 Nov - 01 Dec	Aeroitalia
24 Nov - 01 Dec	Ryanair
28 Nov - 03 Dec	Aeroitalia
27 Nov - 02 Dec	Aeroitalia
30 Nov - 03 Dec	easyJet
29 Nov - 08 Dec	Aeroitalia
28 Nov - 03 Dec	Turkish Airlines	direct
26 Nov - 01 Dec	Turkish Airlines	direct
30 Nov - 08 Dec	easyJet

Also check the deals for one-way flights from Palermo to Istanbul in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Palermo to Istanbul in November from 149€

Return flights