AirHint found the following cheapest return flights from Palermo (PMO) to Istanbul (IST) in November 2025 (see full year).

Return flights

06 Nov - 12 Nov	Ryanair
12 Nov - 14 Nov	Ryanair
06 Nov - 16 Nov	Ryanair
26 Nov - 30 Nov	Ryanair
26 Nov - 29 Nov	Ryanair
21 Nov - 30 Nov	Ryanair
27 Nov - 29 Nov	Ryanair
12 Nov - 18 Nov	Ryanair
27 Nov - 30 Nov	Ryanair
10 Nov - 12 Nov	Ryanair
28 Nov - 01 Dec	Ryanair
30 Nov - 13 Dec	Aeroitalia
23 Nov - 01 Dec	Aeroitalia
30 Nov - 07 Dec	Aeroitalia
25 Nov - 01 Dec	Ryanair
30 Nov - 03 Dec	Aeroitalia
30 Nov - 07 Dec	Turkish Airlines	direct
30 Nov - 03 Dec	Turkish Airlines	direct
26 Nov - 01 Dec	Turkish Airlines

Also check the deals for one-way flights from Palermo to Istanbul in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Palermo to Istanbul in November from 156€

Return flights