AirHint found the following cheapest return flights from Palermo (PMO) to Sao Paulo (GRU) in December 2025 (see full year).

Return flights

01 Dec - 14 Dec	ITA Airways
03 Dec - 15 Dec	ITA Airways
07 Dec - 19 Dec	ITA Airways
09 Dec - 20 Dec	ITA Airways
23 Dec - 30 Dec	ITA Airways
12 Dec - 25 Dec	ITA Airways
09 Dec - 21 Dec	ITA Airways
17 Dec - 01 Jan	ITA Airways
26 Dec - 02 Jan	Vueling Airlines
28 Dec - 11 Jan	Transavia France
26 Dec - 11 Jan	ITA Airways
27 Dec - 11 Jan	ITA Airways
20 Dec - 05 Jan	Vueling Airlines
17 Dec - 02 Jan	Vueling Airlines
21 Dec - 03 Jan	Vueling Airlines
20 Dec - 03 Jan	Vueling Airlines
20 Dec - 04 Jan	Vueling Airlines

Also check the deals for one-way flights from Palermo to Sao Paulo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Palermo to Sao Paulo in December from 879€

Return flights