AirHint found the following cheapest return flights from Chicago (ORD) to Guatemala City (GUA) in September 2025 (see full year).

Return flights

27 Sep - 01 Oct	United
03 Sep - 10 Sep	United
09 Sep - 17 Sep	United
06 Sep - 20 Sep	United
23 Sep - 02 Oct	United
17 Sep - 27 Sep	United
29 Sep - 02 Oct	Spirit Airlines
29 Sep - 04 Oct	Spirit Airlines
25 Sep - 29 Sep	Spirit Airlines
29 Sep - 08 Oct	Spirit Airlines
20 Sep - 23 Sep	Spirit Airlines
08 Sep - 23 Sep	Spirit Airlines
08 Sep - 16 Sep	Spirit Airlines
08 Sep - 27 Sep	Spirit Airlines
22 Sep - 27 Sep	Spirit Airlines
20 Sep - 02 Oct	Spirit Airlines
20 Sep - 04 Oct	Spirit Airlines
27 Sep - 02 Oct	Spirit Airlines
22 Sep - 04 Oct	Spirit Airlines
29 Sep - 14 Oct	Spirit Airlines

Also check the deals for one-way flights from Chicago to Guatemala City in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Chicago to Guatemala City in September from 171€

Return flights