AirHint found the following cheapest return flights from Chicago (ORD) to Guatemala City (GUA) in October 2025 (see full year).

Return flights

22 Oct - 25 Oct	United
01 Oct - 11 Oct	Spirit Airlines
01 Oct - 07 Oct	Spirit Airlines
01 Oct - 02 Oct	Spirit Airlines
14 Oct - 25 Oct	Spirit Airlines
15 Oct - 25 Oct	Spirit Airlines
01 Oct - 18 Oct	Spirit Airlines
01 Oct - 22 Oct	Spirit Airlines
01 Oct - 14 Oct	Spirit Airlines
01 Oct - 04 Oct	Spirit Airlines
22 Oct - 09 Nov	Spirit Airlines
21 Oct - 09 Nov	Spirit Airlines
19 Oct - 09 Nov	Spirit Airlines
23 Oct - 09 Nov	Spirit Airlines

Also check the deals for one-way flights from Chicago to Guatemala City in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Chicago to Guatemala City in October from 207€

Return flights