AirHint found the following cheapest return flights from Chicago (ORD) to Sao Paulo (GRU) in December 2025 (see full year).

Return flights

03 Dec - 10 Dec	Copa
05 Dec - 12 Dec	Spirit Airlines
04 Dec - 10 Dec	Copa
04 Dec - 08 Dec	Copa
08 Dec - 13 Jan	Arajet
29 Dec - 24 Jan	Frontier Airlines
15 Dec - 23 Dec	Arajet
23 Dec - 19 Jan	Frontier Airlines
12 Dec - 16 Dec	Spirit Airlines
13 Dec - 10 Jan	Spirit Airlines
23 Dec - 12 Jan	Frontier Airlines
13 Dec - 11 Jan	Spirit Airlines
29 Dec - 19 Jan	Volaris
13 Dec - 17 Jan	Spirit Airlines
12 Dec - 11 Jan	Spirit Airlines
21 Dec - 16 Jan	Frontier Airlines
03 Dec - 10 Dec	United	direct
22 Dec - 29 Dec	United
15 Dec - 31 Dec	United
20 Dec - 29 Dec	Frontier Airlines

Also check the deals for one-way flights from Chicago to Sao Paulo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Chicago to Sao Paulo in December from 448€

Return flights