AirHint found the following cheapest return flights from Chicago (ORD) to Sao Paulo (GRU) in December 2025 (see full year).

Return flights

02 Dec - 09 Dec	Copa
03 Dec - 10 Dec	Copa
04 Dec - 11 Dec	Copa
09 Dec - 16 Dec	Copa
01 Dec - 08 Dec	United
04 Dec - 11 Dec	United	direct
07 Dec - 14 Dec	Spirit Airlines
05 Dec - 12 Dec	United
08 Dec - 15 Dec	Copa
14 Dec - 21 Dec	Spirit Airlines
28 Dec - 04 Jan	Spirit Airlines
12 Dec - 10 Jan	Copa
27 Dec - 04 Jan	Arajet
31 Dec - 07 Jan	Air Canada
22 Dec - 01 Jan	Arajet
12 Dec - 12 Jan	Avianca
18 Dec - 28 Jan	Frontier Airlines
18 Dec - 19 Jan	Frontier Airlines
25 Dec - 01 Jan	Spirit Airlines
11 Dec - 11 Jan	Air Canada

Also check the deals for one-way flights from Chicago to Sao Paulo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Chicago to Sao Paulo in December from 409€

Return flights