AirHint found the following cheapest return flights from Chicago (ORD) to Rome (FCO) in October 2025 (see full year).

Return flights

09 Oct - 15 Oct	TAP
02 Oct - 15 Oct	TAP
18 Oct - 24 Oct	TAP
16 Oct - 22 Oct	TAP
17 Oct - 24 Oct	TAP
30 Oct - 06 Nov	Icelandair
15 Oct - 17 Nov	Icelandair
30 Oct - 08 Nov	Icelandair
16 Oct - 08 Nov	Icelandair
17 Oct - 08 Nov	Icelandair
19 Oct - 25 Oct	Scandinavian Airlines
28 Oct - 04 Nov	Spirit Airlines
11 Oct - 15 Oct	Scandinavian Airlines
27 Oct - 03 Nov	Icelandair
02 Oct - 03 Nov	TAP
08 Oct - 14 Oct	Frontier Airlines
11 Oct - 17 Oct	Frontier Airlines
11 Oct - 23 Oct	TAP
25 Oct - 01 Nov	Scandinavian Airlines
08 Oct - 01 Nov	Frontier Airlines

Also check the deals for one-way flights from Chicago to Rome in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Chicago to Rome in October from 306€

Return flights