AirHint found the following cheapest return flights from Chicago (ORD) to Rome (FCO) in October 2025 (see full year).

Return flights

04 Oct - 14 Oct	TAP
19 Oct - 04 Nov	TAP
22 Oct - 05 Nov	TAP
31 Oct - 08 Nov	Icelandair
27 Oct - 06 Nov	Air Canada
20 Oct - 05 Nov	Delta
31 Oct - 05 Nov	TAP
03 Oct - 13 Nov	TAP
20 Oct - 04 Nov	SWISS
29 Oct - 02 Nov	Spirit Airlines
22 Oct - 28 Oct	TAP
15 Oct - 28 Oct	Frontier Airlines
10 Oct - 23 Oct	Frontier Airlines
02 Oct - 15 Oct	Spirit Airlines
14 Oct - 19 Oct	Turkish Airlines
07 Oct - 12 Oct	Turkish Airlines
21 Oct - 27 Oct	Spirit Airlines
24 Oct - 03 Nov	United
22 Oct - 30 Oct	Frontier Airlines
16 Oct - 29 Oct	Scandinavian Airlines

Also check the deals for one-way flights from Chicago to Rome in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Rome

Cheap car rent in Rome

Cheapest return flights from Chicago to Rome in October from 306€

Return flights