AirHint found the following cheapest return flights from New York (NYC) to Guayaquil (GYE) in September 2025 (see full year).

Return flights

26 Sep - 29 Sep	Spirit Airlines
09 Sep - 10 Sep	Spirit Airlines
05 Sep - 08 Sep	Spirit Airlines
06 Sep - 08 Sep	Spirit Airlines
18 Sep - 30 Sep	Spirit Airlines
01 Sep - 29 Sep	Copa
27 Sep - 29 Sep	Copa
10 Sep - 22 Sep	Spirit Airlines
15 Sep - 22 Sep	Avianca
25 Sep - 06 Oct	Spirit Airlines
06 Sep - 09 Sep	Spirit Airlines
20 Sep - 12 Oct	Copa
20 Sep - 12 Oct	Avianca	direct
18 Sep - 01 Oct	Frontier Airlines
23 Sep - 01 Oct	Copa

Also check the deals for one-way flights from New York to Guayaquil in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from New York to Guayaquil in September from 329€

Return flights