AirHint found the following cheapest return flights from Milano (MXP) to Santiago (SCL) in October 2025 (see full year).

Return flights

08 Oct - 22 Oct	Delta
13 Oct - 26 Oct	Delta
06 Oct - 15 Oct	Delta
02 Oct - 19 Oct	Delta
25 Oct - 10 Nov	Delta
02 Oct - 18 Oct	Delta
08 Oct - 12 Oct	Delta
15 Oct - 20 Oct	Delta
24 Oct - 07 Nov	Delta
17 Oct - 19 Oct	Delta
19 Oct - 26 Oct	Delta
27 Oct - 25 Nov	Air France
18 Oct - 26 Oct	Delta
26 Oct - 08 Nov	Iberia
18 Oct - 17 Nov	Vueling Airlines
31 Oct - 15 Nov	Iberia

Also check the deals for one-way flights from Milano to Santiago in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Milano to Santiago in October from 701€

Return flights