AirHint found the following cheapest return flights from Minneapolis (MSP) to Rome (FCO) in October 2025 (see full year).

Return flights

24 Oct - 15 Nov	Icelandair
24 Oct - 31 Oct	Frontier Airlines
27 Oct - 03 Nov	Frontier Airlines
26 Oct - 02 Nov	Frontier Airlines
27 Oct - 01 Nov	Sun Country Airlines
28 Oct - 01 Nov	Sun Country Airlines

Also check the deals for one-way flights from Minneapolis to Rome in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Minneapolis to Rome in October from 594€

Return flights