AirHint found the following cheapest return flights from Mexico City (MEX) to Prague (PRG) in December 2025 (see full year).

Return flights

01 Dec - 08 Dec	Viva
14 Dec - 29 Dec	Volaris
18 Dec - 29 Dec	Volaris
14 Dec - 31 Dec	Volaris
22 Dec - 29 Dec	Viva
18 Dec - 05 Jan	Volaris
31 Dec - 10 Jan	Lufthansa
22 Dec - 05 Jan	Aeromexico
16 Dec - 30 Dec	Volaris
29 Dec - 05 Jan	Volaris
21 Dec - 28 Dec	Aeromexico
20 Dec - 04 Jan	Aeromexico
19 Dec - 05 Jan	Aeromexico
18 Dec - 02 Jan	Volaris
19 Dec - 26 Dec	Aeromexico
19 Dec - 04 Jan	Aeromexico
17 Dec - 02 Jan	Aeromexico
15 Dec - 31 Dec	KLM
14 Dec - 01 Jan	Air France
18 Dec - 25 Dec	Volaris

Also check the deals for one-way flights from Mexico City to Prague in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Prague

Cheap car rent in Prague

Cheapest return flights from Mexico City to Prague in December from 878€

Return flights