AirHint found the following cheapest return flights from Mexico City (MEX) to Prague (PRG) in December 2025 (see full year).

Return flights

09 Dec - 16 Dec	Iberia
01 Dec - 31 Dec	Air France
08 Dec - 15 Dec	Iberia
01 Dec - 15 Dec	Iberia
01 Dec - 11 Dec	Air France
09 Dec - 15 Dec	Iberia
17 Dec - 31 Dec	Air France
31 Dec - 07 Jan	British Airways
16 Dec - 30 Dec	Lufthansa
20 Dec - 02 Jan	Air France
19 Dec - 27 Dec	British Airways
19 Dec - 06 Jan	British Airways
20 Dec - 10 Jan	British Airways
26 Dec - 05 Jan	British Airways
19 Dec - 04 Jan	British Airways
22 Dec - 26 Dec	Iberia
26 Dec - 02 Jan	British Airways

Also check the deals for one-way flights from Mexico City to Prague in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Prague in December from 735€

Return flights