AirHint found the following cheapest return flights from Mexico City (MEX) to Sao Paulo (GRU) in September 2025 (see full year).

Return flights

16 Sep - 22 Sep	Arajet
02 Sep - 08 Sep	Arajet
30 Sep - 06 Oct	Arajet
11 Sep - 22 Sep	Arajet
04 Sep - 19 Sep	Arajet
14 Sep - 22 Sep	Arajet
14 Sep - 24 Sep	Arajet
10 Sep - 19 Sep	Avianca
01 Sep - 20 Sep	Avianca
02 Sep - 14 Sep	Avianca
08 Sep - 15 Sep	Avianca
07 Sep - 07 Oct	Avianca
22 Sep - 22 Oct	LATAM Airlines Group	direct
24 Sep - 01 Oct	Copa
27 Sep - 04 Oct	Copa
27 Sep - 11 Oct	Copa
20 Sep - 02 Oct	Copa
21 Sep - 02 Oct	Copa
18 Sep - 02 Oct	Copa
24 Sep - 01 Oct	LATAM Airlines Group	direct

Also check the deals for one-way flights from Mexico City to Sao Paulo in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Sao Paulo in September from 364€

Return flights