AirHint found the following cheapest return flights from Mexico City (MEX) to Sao Paulo (GRU) in October 2025 (see full year).

Return flights

04 Oct - 22 Oct	Arajet
02 Oct - 08 Oct	Arajet
01 Oct - 08 Oct	Arajet
01 Oct - 06 Oct	Arajet
02 Oct - 06 Oct	Arajet
08 Oct - 18 Oct	Avianca
09 Oct - 17 Oct	Avianca
10 Oct - 19 Oct	Avianca
13 Oct - 20 Oct	Avianca
14 Oct - 20 Oct	Avianca
24 Oct - 09 Nov	Avianca
26 Oct - 10 Nov	Avianca
17 Oct - 09 Nov	Avianca
27 Oct - 05 Nov	Avianca
17 Oct - 10 Nov	Avianca
20 Oct - 01 Nov	Avianca
29 Oct - 03 Nov	Copa
29 Oct - 30 Nov	LATAM Airlines Group	direct
29 Oct - 03 Nov	Aeromexico	direct
17 Oct - 09 Nov	LATAM Airlines Group	direct

Also check the deals for one-way flights from Mexico City to Sao Paulo in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Sao Paulo in October from 366€

Return flights