AirHint found the following cheapest return flights from Mexico City (MEX) to Sao Paulo (GRU) in October 2025 (see full year).

Return flights

23 Oct - 05 Nov	Arajet
21 Oct - 05 Nov	Arajet
22 Oct - 05 Nov	Avianca
22 Oct - 30 Nov	Copa
27 Oct - 03 Nov	Copa
28 Oct - 05 Nov	Copa
21 Oct - 03 Nov	Avianca
30 Oct - 30 Nov	Copa
20 Oct - 30 Nov	Copa
28 Oct - 09 Nov	Copa
22 Oct - 30 Oct	LATAM Airlines Group
21 Oct - 30 Oct	LATAM Airlines Group
15 Oct - 31 Oct	LATAM Airlines Group
20 Oct - 27 Oct	GOL Linhas Aéreas
21 Oct - 31 Oct	LATAM Airlines Group
22 Oct - 31 Oct	LATAM Airlines Group
23 Oct - 30 Oct	LATAM Airlines Group
16 Oct - 26 Oct	Copa
20 Oct - 29 Oct	GOL Linhas Aéreas
22 Oct - 29 Oct	Avianca

Also check the deals for one-way flights from Mexico City to Sao Paulo in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Sao Paulo in October from 377€

Return flights