AirHint found the following cheapest return flights from Melbourne (MEL) to Santiago (SCL) in September 2025 (see full year).

Return flights

01 Sep - 08 Sep	LATAM Airlines Group
08 Sep - 22 Sep	LATAM Airlines Group
03 Sep - 03 Oct	LATAM Airlines Group
03 Sep - 03 Oct	LATAM Airlines Group	direct
01 Sep - 05 Oct	LATAM Airlines Group	direct
01 Sep - 30 Sep	LATAM Airlines Group	direct
11 Sep - 02 Oct	Qantas
01 Sep - 04 Oct	Jetstar
03 Sep - 27 Sep	LATAM Airlines Group
26 Sep - 31 Oct	LATAM Airlines Group
22 Sep - 26 Sep	LATAM Airlines Group
27 Sep - 17 Oct	Qantas
12 Sep - 24 Oct	LATAM Airlines Group
18 Sep - 28 Sep	Qantas
20 Sep - 19 Oct	LATAM Airlines Group
03 Sep - 20 Oct	LATAM Airlines Group
21 Sep - 25 Sep	Qantas
24 Sep - 29 Sep	LATAM Airlines Group
15 Sep - 22 Sep	Qantas
06 Sep - 30 Sep	Qatar Airways

Also check the deals for one-way flights from Melbourne to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Melbourne to Santiago in September from 1076€

Return flights