AirHint found the following cheapest return flights from Melbourne (MEL) to Santiago (SCL) in September 2025 (see full year).

Return flights

01 Sep - 21 Sep	LATAM Airlines Group	direct
09 Sep - 16 Sep	Qantas
29 Sep - 19 Oct	LATAM Airlines Group	direct
03 Sep - 02 Oct	LATAM Airlines Group
04 Sep - 02 Oct	LATAM Airlines Group
17 Sep - 14 Oct	LATAM Airlines Group	direct
12 Sep - 24 Oct	Cathay Pacific
15 Sep - 19 Sep	Qantas
15 Sep - 21 Sep	LATAM Airlines Group
10 Sep - 30 Sep	Qantas
05 Sep - 03 Oct	Qantas
06 Sep - 03 Oct	Qantas
11 Sep - 30 Sep	LATAM Airlines Group
06 Sep - 02 Oct	Qantas
10 Sep - 30 Sep	LATAM Airlines Group	direct
14 Sep - 09 Oct	LATAM Airlines Group
13 Sep - 09 Oct	LATAM Airlines Group
24 Sep - 28 Sep	LATAM Airlines Group
26 Sep - 30 Sep	LATAM Airlines Group

Also check the deals for one-way flights from Melbourne to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Melbourne to Santiago in September from 1184€

Return flights