AirHint found the following cheapest return flights from Chicago (MDW) to Istanbul (IST) in November 2025 (see full year).

Return flights

26 Nov - 09 Dec	KLM
20 Nov - 24 Nov	Frontier Airlines
28 Nov - 20 Dec	Frontier Airlines
22 Nov - 27 Nov	Frontier Airlines
28 Nov - 11 Dec	Delta
17 Nov - 08 Dec	Delta
25 Nov - 28 Nov	Frontier Airlines
23 Nov - 28 Nov	Frontier Airlines
10 Nov - 06 Dec	Frontier Airlines
20 Nov - 28 Nov	Frontier Airlines
15 Nov - 06 Dec	Frontier Airlines
11 Nov - 25 Nov	KLM
14 Nov - 06 Dec	KLM
22 Nov - 26 Nov	KLM
16 Nov - 21 Nov	Delta
22 Nov - 13 Dec	KLM
23 Nov - 27 Nov	Delta
27 Nov - 20 Dec	Frontier Airlines
24 Nov - 29 Nov	Delta

Also check the deals for one-way flights from Chicago to Istanbul in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Chicago to Istanbul in November from 762€

Return flights