AirHint found the following cheapest return flights from Chicago (MDW) to Sao Paulo (GRU) in December 2025 (see full year).

Return flights

23 Dec - 13 Jan	Delta
08 Dec - 29 Dec	Delta
12 Dec - 13 Jan	Delta
13 Dec - 20 Dec	Delta
12 Dec - 11 Jan	Delta
18 Dec - 25 Dec	Delta
29 Dec - 05 Jan	Delta
30 Dec - 06 Jan	Delta
20 Dec - 18 Jan	Delta
19 Dec - 31 Jan	Delta
12 Dec - 10 Jan	Delta
19 Dec - 27 Dec	Delta
20 Dec - 29 Dec	Delta
31 Dec - 05 Jan	Delta
16 Dec - 06 Jan	Delta
21 Dec - 27 Dec	Delta

Also check the deals for one-way flights from Chicago to Sao Paulo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Chicago to Sao Paulo in December from 949€

Return flights