AirHint found the following cheapest return flights from Rio Negro (MDE) to Quito (UIO) in December 2025 (see full year).

Return flights

02 Dec - 10 Dec	LATAM Airlines Group
30 Dec - 02 Jan	Avianca
31 Dec - 03 Jan	LATAM Airlines Group
31 Dec - 03 Jan	Avianca	direct
27 Dec - 05 Jan	Avianca	direct
23 Dec - 04 Jan	LATAM Airlines Group
24 Dec - 05 Jan	LATAM Airlines Group
24 Dec - 05 Jan	Avianca	direct
24 Dec - 04 Jan	Avianca	direct
24 Dec - 04 Jan	LATAM Airlines Group
26 Dec - 04 Jan	Avianca

Also check the deals for one-way flights from Rio Negro to Quito in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rio Negro to Quito in December from 257€

Return flights