AirHint found the following cheapest return flights from Rio Negro (MDE) to Santiago (SCL) in September 2025 (see full year).

Return flights

29 Sep - 01 Oct	JetSmart
15 Sep - 01 Oct	JetSmart
14 Sep - 01 Oct	JetSmart
08 Sep - 10 Sep	JetSmart
08 Sep - 11 Sep	JetSmart
29 Sep - 08 Oct	JetSmart
15 Sep - 30 Sep	JetSmart
15 Sep - 25 Sep	JetSmart
08 Sep - 25 Sep	JetSmart
29 Sep - 10 Oct	JetSmart
15 Sep - 20 Sep	JetSmart
05 Sep - 08 Sep	JetSmart
08 Sep - 20 Sep	JetSmart
29 Sep - 19 Oct	JetSmart
23 Sep - 01 Oct	JetSmart
15 Sep - 24 Sep	JetSmart
07 Sep - 10 Sep	JetSmart
19 Sep - 01 Oct	JetSmart
29 Sep - 16 Oct	JetSmart
29 Sep - 17 Oct	JetSmart

Also check the deals for one-way flights from Rio Negro to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rio Negro to Santiago in September from 210€

Return flights