AirHint found the following cheapest return flights from Rio Negro (MDE) to Santiago (SCL) in September 2025 (see full year).

Return flights

29 Sep - 06 Oct	JetSmart
27 Sep - 06 Oct	JetSmart
30 Sep - 06 Oct	JetSmart
29 Sep - 01 Oct	JetSmart
01 Sep - 07 Sep	JetSmart
29 Sep - 15 Oct	JetSmart
16 Sep - 06 Oct	JetSmart
15 Sep - 24 Sep	JetSmart
27 Sep - 01 Oct	JetSmart
15 Sep - 22 Sep	JetSmart
27 Sep - 15 Oct	JetSmart
15 Sep - 01 Oct	JetSmart
15 Sep - 17 Sep	JetSmart
15 Sep - 21 Sep	JetSmart
30 Sep - 01 Oct	JetSmart
01 Sep - 17 Sep	JetSmart
01 Sep - 21 Sep	JetSmart
16 Sep - 24 Sep	JetSmart
16 Sep - 22 Sep	JetSmart
16 Sep - 17 Sep	JetSmart

Also check the deals for one-way flights from Rio Negro to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rio Negro to Santiago in September from 278€

Return flights