AirHint found the following cheapest return flights from Rio Negro (MDE) to Santiago (SCL) in April 2026 (see full year).

Return flights

24 Apr - 08 May	JetSmart	direct
24 Apr - 09 May	JetSmart	direct
24 Apr - 15 May	JetSmart	direct
24 Apr - 12 May	JetSmart	direct
25 Apr - 08 May	JetSmart
25 Apr - 09 May	JetSmart
21 Apr - 08 May	JetSmart
21 Apr - 09 May	JetSmart
23 Apr - 08 May	JetSmart
23 Apr - 09 May	JetSmart
12 Apr - 24 Apr	JetSmart	direct
09 Apr - 13 Apr	JetSmart	direct
09 Apr - 13 Apr	JetSmart
21 Apr - 24 Apr	JetSmart
22 Apr - 24 Apr	JetSmart
09 Apr - 24 Apr	JetSmart
09 Apr - 24 Apr	JetSmart	direct
09 Apr - 11 Apr	JetSmart
09 Apr - 11 Apr	JetSmart	direct
12 Apr - 14 Apr	JetSmart	direct

Also check the deals for one-way flights from Rio Negro to Santiago in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rio Negro to Santiago in April from 239€

Return flights