AirHint found the following cheapest return flights from Rio Negro (MDE) to Santiago (SCL) in December 2025 (see full year).

Return flights

15 Dec - 30 Dec	JetSmart
22 Dec - 30 Dec	JetSmart	direct
05 Dec - 15 Dec	JetSmart
05 Dec - 19 Dec	JetSmart
05 Dec - 15 Dec	JetSmart	direct
05 Dec - 19 Dec	JetSmart	direct
05 Dec - 09 Dec	JetSmart
05 Dec - 23 Dec	JetSmart
05 Dec - 22 Dec	JetSmart
17 Dec - 30 Dec	JetSmart
22 Dec - 08 Jan	JetSmart
15 Dec - 01 Jan	JetSmart
22 Dec - 01 Jan	JetSmart
22 Dec - 12 Jan	JetSmart
23 Dec - 08 Jan	JetSmart
22 Dec - 09 Jan	JetSmart	direct
17 Dec - 01 Jan	JetSmart
23 Dec - 01 Jan	JetSmart
15 Dec - 02 Jan	JetSmart
22 Dec - 02 Jan	JetSmart

Also check the deals for one-way flights from Rio Negro to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rio Negro to Santiago in December from 231€

Return flights