AirHint found the following cheapest return flights from Rio Negro (MDE) to Santiago (SCL) in December 2026 (see full year).
Return flights
| 18 Dec - 25 Dec | JetSmart | direct | |
| 14 Dec - 21 Dec | JetSmart | direct | |
| 06 Dec - 11 Dec | JetSmart | direct | |
| 05 Dec - 10 Dec | Avianca | ||
| 15 Dec - 22 Dec | LATAM Airlines Group | ||
| 21 Dec - 29 Dec | Copa | ||
| 26 Dec - 03 Jan | Copa |
Also check the deals for one-way flights from Rio Negro to Santiago in December.
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