AirHint found the following cheapest return flights from Rio Negro (MDE) to Santiago (SCL) in November 2025 (see full year).

Return flights

06 Nov - 09 Nov	Avianca
06 Nov - 07 Nov	Avianca
20 Nov - 24 Nov	LATAM Airlines Group
08 Nov - 16 Nov	LATAM Airlines Group
22 Nov - 25 Nov	JetSmart
22 Nov - 09 Dec	JetSmart
22 Nov - 24 Nov	JetSmart
02 Nov - 19 Nov	JetSmart
13 Nov - 23 Nov	Avianca
02 Nov - 21 Nov	JetSmart
22 Nov - 04 Dec	JetSmart
22 Nov - 02 Dec	JetSmart
12 Nov - 18 Nov	LATAM Airlines Group
30 Nov - 09 Dec	JetSmart
24 Nov - 09 Dec	Avianca
22 Nov - 11 Dec	JetSmart
11 Nov - 02 Dec	JetSmart
22 Nov - 05 Dec	JetSmart
30 Nov - 04 Dec	JetSmart
30 Nov - 02 Dec	JetSmart

Also check the deals for one-way flights from Rio Negro to Santiago in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rio Negro to Santiago in November from 315€

Return flights