AirHint found the following cheapest return flights from Rio Negro (MDE) to Cancun (CUN) in September 2025 (see full year).

Return flights

02 Sep - 09 Sep	Copa
22 Sep - 30 Sep	Copa
08 Sep - 14 Sep	Copa
08 Sep - 12 Sep	Copa
23 Sep - 29 Sep	Copa
01 Sep - 06 Sep	Copa
02 Sep - 07 Sep	Copa
04 Sep - 08 Sep	Copa
09 Sep - 16 Sep	Copa
11 Sep - 18 Sep	Copa
26 Sep - 01 Oct	Copa
29 Sep - 03 Oct	Copa
26 Sep - 01 Oct	Avianca	direct
29 Sep - 03 Oct	Avianca	direct

Also check the deals for one-way flights from Rio Negro to Cancun in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rio Negro to Cancun in September from 307€

Return flights