AirHint found the following cheapest return flights from Madrid (MAD) to Santa Cruz (VVI) in October 2026 (see full year).

Return flights

07 Oct - 27 Oct	Avianca
07 Oct - 25 Oct	Avianca
02 Oct - 17 Oct	Avianca
01 Oct - 22 Oct	Avianca
01 Oct - 08 Oct	Avianca
02 Oct - 31 Oct	Avianca
01 Oct - 15 Oct	Avianca
01 Oct - 31 Oct	Avianca
01 Oct - 30 Oct	Avianca
09 Oct - 27 Oct	Avianca
31 Oct - 07 Nov	Avianca
31 Oct - 08 Nov	Avianca
31 Oct - 09 Nov	Avianca
21 Oct - 03 Nov	Avianca
21 Oct - 03 Nov	Iberia	direct
31 Oct - 07 Nov	Air Europa	direct

Also check the deals for one-way flights from Madrid to Santa Cruz in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Santa Cruz in October from 650€

Return flights