AirHint found the following cheapest return flights from Madrid (MAD) to Santiago (SCL) in September 2026 (see full year).

Return flights

11 Sep - 20 Sep	Iberia
07 Sep - 21 Sep	Iberia
01 Sep - 17 Sep	Iberia
01 Sep - 24 Sep	Iberia
16 Sep - 04 Oct	Iberia	direct
06 Sep - 21 Sep	Iberia	direct
10 Sep - 20 Sep	Iberia	direct
01 Sep - 30 Sep	Iberia	direct
04 Sep - 13 Sep	Avianca
25 Sep - 02 Oct	Avianca
01 Sep - 15 Sep	Iberia	direct

Also check the deals for one-way flights from Madrid to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Santiago in September from 895€

Return flights