AirHint found the following cheapest return flights from Madrid (MAD) to Santiago (SCL) in September 2026 (see full year).

Return flights

11 Sep - 21 Sep	Delta
02 Sep - 21 Sep	Delta
07 Sep - 23 Sep	Delta
16 Sep - 07 Oct	Delta
07 Sep - 14 Sep	Delta
01 Sep - 30 Sep	Delta
02 Sep - 14 Sep	Delta
11 Sep - 30 Sep	Delta
07 Sep - 28 Sep	Delta
11 Sep - 27 Sep	Iberia	direct
16 Sep - 29 Sep	Iberia	direct
13 Sep - 04 Oct	Iberia	direct
16 Sep - 07 Oct	Iberia	direct
14 Sep - 31 Oct	Iberia	direct
25 Sep - 16 Oct	Delta
28 Sep - 05 Oct	Iberia	direct

Also check the deals for one-way flights from Madrid to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Santiago in September from 700€

Return flights