AirHint found the following cheapest return flights from Madrid (MAD) to Santiago (SCL) in October 2026 (see full year).

Return flights

01 Oct - 14 Oct	Avianca
08 Oct - 25 Oct	Avianca
01 Oct - 18 Oct	Avianca
12 Oct - 31 Oct	Avianca
07 Oct - 14 Oct	Avianca
01 Oct - 17 Oct	Avianca
22 Oct - 01 Nov	Avianca
09 Oct - 13 Nov	Iberia
09 Oct - 16 Oct	Iberia	direct
12 Oct - 31 Oct	Iberia	direct
07 Oct - 14 Oct	Iberia	direct
31 Oct - 15 Nov	Iberia	direct
22 Oct - 01 Nov	Iberia	direct
30 Oct - 15 Nov	Iberia	direct
14 Oct - 23 Oct	Iberia	direct

Also check the deals for one-way flights from Madrid to Santiago in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Santiago in October from 901€

Return flights