AirHint found the following cheapest return flights from Madrid (MAD) to Istanbul (SAW) in October 2025 (see full year).

Return flights

15 Oct - 19 Nov	Wizz Air Malta
28 Oct - 09 Nov	Air Europa
08 Oct - 22 Oct	Ryanair
28 Oct - 04 Nov	Wizz Air Malta
28 Oct - 03 Nov	Wizz Air Malta
25 Oct - 04 Nov	Volotea
14 Oct - 30 Oct	Wizz Air Malta
29 Oct - 07 Nov	easyJet
29 Oct - 03 Nov	Wizz Air Malta
29 Oct - 04 Nov	easyJet
01 Oct - 22 Oct	Wizz Air Malta
07 Oct - 15 Oct	Wizz Air Malta
05 Oct - 14 Oct	Wizz Air Malta
27 Oct - 05 Nov	easyJet
23 Oct - 06 Nov	Wizz Air Malta
01 Oct - 07 Oct	easyJet
09 Oct - 22 Oct	Wizz Air Malta
22 Oct - 28 Oct	Wizz Air Malta
28 Oct - 30 Oct	Wizz Air Malta
22 Oct - 29 Oct	Wizz Air Malta

Also check the deals for one-way flights from Madrid to Istanbul in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Istanbul in October from 140€

Return flights