AirHint found the following cheapest return flights from Madrid (MAD) to Guatemala City (GUA) in September 2025 (see full year).

Return flights

09 Sep - 23 Sep	United
16 Sep - 30 Sep	United
24 Sep - 05 Oct	United
23 Sep - 04 Oct	United
23 Sep - 05 Oct	Lufthansa
24 Sep - 08 Oct	United
06 Sep - 28 Sep	United
21 Sep - 30 Sep	United
13 Sep - 28 Sep	United
26 Sep - 15 Oct	United
10 Sep - 24 Sep	United
06 Sep - 15 Sep	United
15 Sep - 15 Oct	United
15 Sep - 29 Sep	United
13 Sep - 04 Oct	United
19 Sep - 04 Oct	United
08 Sep - 22 Sep	United
04 Sep - 19 Sep	United
25 Sep - 14 Oct	United
11 Sep - 03 Oct	United

Also check the deals for one-way flights from Madrid to Guatemala City in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Guatemala City in September from 535€

Return flights