AirHint found the following cheapest return flights from Madrid (MAD) to Guatemala City (GUA) in October 2025 (see full year).

Return flights

20 Oct - 07 Nov	Air Canada
13 Oct - 26 Oct	Air Canada
06 Oct - 14 Oct	Air Canada
06 Oct - 19 Oct	Air Canada
02 Oct - 12 Oct	United
23 Oct - 01 Nov	United
22 Oct - 06 Nov	United
02 Oct - 14 Oct	Air Canada
23 Oct - 07 Nov	United
10 Oct - 19 Oct	Air Canada
09 Oct - 23 Oct	United
10 Oct - 18 Oct	United
24 Oct - 05 Nov	United
26 Oct - 09 Nov	United
29 Oct - 14 Nov	United
22 Oct - 04 Nov	United
24 Oct - 08 Nov	United
24 Oct - 01 Nov	United
02 Oct - 09 Oct	United
01 Oct - 15 Oct	United

Also check the deals for one-way flights from Madrid to Guatemala City in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Guatemala City

Cheap car rent in Guatemala City

Cheapest return flights from Madrid to Guatemala City in October from 501€

Return flights