AirHint found the following cheapest return flights from Lyon (LYS) to Prague (PRG) in April 2026 (see full year).

Return flights

19 Apr - 22 Apr	easyJet	direct
12 Apr - 15 Apr	easyJet	direct
20 Apr - 23 Apr	easyJet
08 Apr - 11 Apr	easyJet
05 Apr - 19 Apr	easyJet	direct
10 Apr - 12 Apr	easyJet	direct
12 Apr - 22 Apr	Vueling Airlines
03 Apr - 22 Apr	Vueling Airlines
04 Apr - 18 Apr	KLM
05 Apr - 22 Apr	Vueling Airlines

Also check the deals for one-way flights from Lyon to Prague in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Lyon to Prague in April from 74€

Return flights