AirHint found the following cheapest return flights from Lisbon (LIS) to Sao Tome (TMS) in September 2025 (see full year).

Return flights

23 Sep - 08 Oct	TAAG Angola Airlines
23 Sep - 29 Sep	TAAG Angola Airlines
21 Sep - 26 Sep	TAAG Angola Airlines
16 Sep - 26 Sep	TAP
16 Sep - 01 Oct	TAP
16 Sep - 24 Sep	TAP	direct
16 Sep - 29 Sep	TAP
30 Sep - 13 Oct	TAP
16 Sep - 01 Oct	TAP	direct
30 Sep - 15 Oct	TAP
10 Sep - 29 Sep	TAP
09 Sep - 01 Oct	TAP	direct
19 Sep - 26 Sep	TAP
19 Sep - 22 Sep	TAP
05 Sep - 26 Sep	TAP
13 Sep - 19 Sep	TAP
02 Sep - 01 Oct	TAP	direct
07 Sep - 03 Oct	TAP
30 Sep - 25 Oct	TAP	direct
30 Sep - 11 Oct	TAP	direct

Also check the deals for one-way flights from Lisbon to Sao Tome in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Lisbon to Sao Tome in September from 514€

Return flights