AirHint found the following cheapest return flights from Lisbon (LIS) to Prague (PRG) in October 2025 (see full year).

Return flights

22 Oct - 29 Oct	easyJet
30 Oct - 04 Nov	easyJet
08 Oct - 14 Oct	easyJet
30 Oct - 01 Nov	easyJet
22 Oct - 30 Oct	easyJet
30 Oct - 03 Nov	easyJet
09 Oct - 14 Oct	easyJet
24 Oct - 29 Oct	easyJet
22 Oct - 05 Nov	Vueling Airlines
22 Oct - 04 Nov	Vueling Airlines
09 Oct - 11 Oct	Ryanair
07 Oct - 14 Oct	easyJet
07 Oct - 11 Oct	Ryanair
03 Oct - 11 Oct	easyJet
10 Oct - 14 Oct	easyJet
22 Oct - 12 Nov	Vueling Airlines
24 Oct - 01 Nov	easyJet
22 Oct - 03 Nov	Vueling Airlines
29 Oct - 02 Nov	Ryanair
27 Oct - 01 Nov	easyJet

Also check the deals for one-way flights from Lisbon to Prague in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Lisbon to Prague in October from 114€

Return flights