AirHint found the following cheapest return flights from Lisbon (LIS) to Prague (PRG) in October 2025 (see full year).

Return flights

19 Oct - 28 Oct	easyJet
22 Oct - 28 Oct	easyJet
13 Oct - 20 Oct	easyJet
15 Oct - 20 Oct	easyJet
24 Oct - 28 Oct	easyJet
22 Oct - 29 Oct	easyJet
18 Oct - 20 Oct	easyJet
26 Oct - 29 Oct	easyJet
11 Oct - 18 Oct	easyJet
02 Oct - 06 Oct	easyJet
28 Oct - 04 Nov	easyJet
30 Oct - 01 Nov	easyJet
22 Oct - 05 Nov	Vueling Airlines
22 Oct - 01 Nov	Vueling Airlines
22 Oct - 12 Nov	Vueling Airlines
22 Oct - 04 Nov	Vueling Airlines
31 Oct - 02 Nov	easyJet
21 Oct - 05 Nov	Vueling Airlines
21 Oct - 01 Nov	Vueling Airlines
21 Oct - 04 Nov	Vueling Airlines

Also check the deals for one-way flights from Lisbon to Prague in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Lisbon to Prague in October from 115€

Return flights