AirHint found the following cheapest return flights from Lisbon (LIS) to Prague (PRG) in October 2025 (see full year).

Return flights

08 Oct - 15 Oct	easyJet	direct
15 Oct - 17 Oct	easyJet	direct
24 Oct - 28 Oct	easyJet	direct
31 Oct - 11 Nov	easyJet
22 Oct - 28 Oct	Vueling Airlines
30 Oct - 11 Nov	easyJet
06 Oct - 15 Oct	easyJet
07 Oct - 15 Oct	easyJet
31 Oct - 04 Nov	easyJet
20 Oct - 28 Oct	easyJet
04 Oct - 07 Oct	easyJet
15 Oct - 22 Oct	easyJet	direct
22 Oct - 28 Oct	easyJet	direct
22 Oct - 04 Nov	Vueling Airlines
29 Oct - 11 Nov	easyJet
29 Oct - 04 Nov	easyJet
22 Oct - 12 Nov	Vueling Airlines
29 Oct - 01 Nov	easyJet
22 Oct - 05 Nov	Vueling Airlines
22 Oct - 06 Nov	Vueling Airlines

Also check the deals for one-way flights from Lisbon to Prague in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Lisbon to Prague in October from 120€

Return flights