AirHint found the following cheapest return flights from Milan (LIN) to Panama City (PTY) in December 2025 (see full year).

Return flights

09 Dec - 16 Dec	Air France
01 Dec - 10 Dec	Air France
14 Dec - 29 Dec	Iberia
13 Dec - 29 Dec	Iberia
14 Dec - 30 Dec	Air France
25 Dec - 28 Dec	KLM
29 Dec - 10 Jan	Delta
23 Dec - 05 Jan	KLM
26 Dec - 05 Jan	KLM
30 Dec - 09 Jan	Air France
21 Dec - 31 Dec	Iberia
18 Dec - 25 Dec	Air France
30 Dec - 07 Jan	Iberia
20 Dec - 28 Dec	KLM
20 Dec - 29 Dec	KLM
23 Dec - 11 Jan	Air France
27 Dec - 11 Jan	KLM
30 Dec - 10 Jan	Iberia
28 Dec - 10 Jan	Iberia
26 Dec - 04 Jan	KLM

Also check the deals for one-way flights from Milan to Panama City in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Milan to Panama City in December from 739€

Return flights