AirHint found the following cheapest return flights from Keflavik (KEF) to Prague (PRG) in September 2025 (see full year).

Return flights

08 Sep - 12 Sep	Fly Play
16 Sep - 20 Sep	Wizz Air
29 Sep - 06 Oct	KLM
04 Sep - 12 Sep	Fly Play
25 Sep - 29 Sep	Fly Play
18 Sep - 25 Sep	Wizz Air
27 Sep - 04 Oct	Wizz Air
24 Sep - 29 Sep	Fly Play
17 Sep - 21 Sep	Wizz Air
23 Sep - 29 Sep	Wizz Air
26 Sep - 30 Sep	Fly Play
22 Sep - 28 Sep	Scandinavian Airlines
28 Sep - 05 Oct	Wizz Air Malta
28 Sep - 05 Oct	Fly Play	direct
29 Sep - 06 Oct	Icelandair	direct

Also check the deals for one-way flights from Keflavik to Prague in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Keflavik to Prague in September from 203€

Return flights