AirHint found the following cheapest return flights from Santorini (Thira) (JTR) to Prague (PRG) in October 2025 (see full year).

Return flights

06 Oct - 10 Oct	Aegean Airlines
24 Oct - 11 Nov	SKY express
10 Oct - 15 Oct	SKY express
10 Oct - 11 Oct	SKY express
04 Oct - 15 Oct	SKY express
03 Oct - 15 Oct	SKY express
13 Oct - 15 Oct	SKY express
04 Oct - 11 Oct	SKY express
03 Oct - 11 Oct	SKY express
25 Oct - 11 Nov	SKY express
06 Oct - 15 Oct	SKY express
01 Oct - 15 Oct	SKY express
28 Oct - 11 Nov	SKY express

Also check the deals for one-way flights from Santorini (Thira) to Prague in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santorini (Thira) to Prague in October from 260€

Return flights