AirHint found the following cheapest return flights from Istanbul (IST) to Karachi (KHI) in September 2025 (see full year).

Return flights

20 Sep - 27 Sep	Pegasus Airlines
20 Sep - 04 Oct	Pegasus Airlines
20 Sep - 05 Oct	Pegasus Airlines
29 Sep - 06 Oct	Pegasus Airlines
02 Sep - 06 Oct	Flynas
28 Sep - 26 Oct	Pegasus Airlines
25 Sep - 24 Oct	Pegasus Airlines
12 Sep - 12 Oct	flyadeal
09 Sep - 14 Sep	Gulf Air
30 Sep - 26 Oct	Gulf Air
15 Sep - 29 Sep	Pegasus Airlines
02 Sep - 02 Oct	Gulf Air
14 Sep - 28 Sep	Gulf Air
15 Sep - 26 Oct	Gulf Air
16 Sep - 30 Sep	Pegasus Airlines
02 Sep - 17 Sep	Flynas
12 Sep - 14 Sep	flyadeal
09 Sep - 16 Sep	Gulf Air
15 Sep - 30 Sep	Gulf Air
08 Sep - 18 Sep	Gulf Air

Also check the deals for one-way flights from Istanbul to Karachi in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Istanbul to Karachi in September from 243€

Return flights