AirHint found the following cheapest return flights from Istanbul (IST) to Karachi (KHI) in December 2025 (see full year).

Return flights

16 Dec - 01 Jan	Flynas
16 Dec - 05 Jan	Flynas
16 Dec - 06 Jan	Flynas
01 Dec - 25 Dec	Gulf Air
14 Dec - 31 Dec	Air Arabia
01 Dec - 25 Dec	Pegasus Airlines	direct
12 Dec - 11 Jan	Pegasus Airlines	direct
16 Dec - 05 Jan	Pegasus Airlines	direct
16 Dec - 06 Jan	Pegasus Airlines	direct
16 Dec - 01 Jan	PIA	direct
14 Dec - 31 Dec	Turkish Airlines	direct

Also check the deals for one-way flights from Istanbul to Karachi in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Istanbul to Karachi in December from 313€

Return flights