AirHint found the following cheapest return flights from Istanbul (IST) to Sao Paulo (GRU) in May 2026 (see full year).

Return flights

27 May - 12 Jun	Air Europa
09 May - 28 May	Air Europa
18 May - 25 May	Air Europa
20 May - 27 May	Air Europa
14 May - 21 May	Air Europa
17 May - 24 May	Royal Air Maroc
15 May - 22 May	Air Europa
07 May - 21 May	Air Europa
19 May - 26 May	Air Europa
13 May - 26 May	Air Europa
08 May - 15 May	Air Europa
20 May - 11 Jun	Air Europa
23 May - 03 Jun	KLM
22 May - 14 Jun	KLM
24 May - 02 Jun	KLM
23 May - 04 Jun	Air Europa
22 May - 01 Jun	KLM
24 May - 04 Jun	KLM
23 May - 03 Jun	Turkish Airlines	direct
24 May - 02 Jun	Turkish Airlines	direct

Also check the deals for one-way flights from Istanbul to Sao Paulo in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Istanbul to Sao Paulo in May from 658€

Return flights