AirHint found the following cheapest return flights from Istanbul (IST) to Sao Paulo (GRU) in May 2026 (see full year).

Return flights

13 May - 22 May	Royal Air Maroc
14 May - 01 Jun	Air Europa
13 May - 25 May	Air Europa
07 May - 14 May	Air Europa
15 May - 31 May	Air Europa
20 May - 27 May	Air Europa
09 May - 19 May	Air Europa
15 May - 30 Jun	KLM
22 May - 01 Jun	Air Europa
04 May - 20 May	Air Europa
15 May - 22 May	Air Europa
10 May - 21 May	Air Europa
26 May - 07 Jun	Air Europa
26 May - 31 May	Air Europa
14 May - 01 Jun	Turkish Airlines	direct
26 May - 07 Jun	Turkish Airlines	direct
23 May - 01 Jun	Turkish Airlines	direct
15 May - 30 Jun	Turkish Airlines	direct
22 May - 01 Jun	Turkish Airlines	direct

Also check the deals for one-way flights from Istanbul to Sao Paulo in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Istanbul to Sao Paulo in May from 679€

Return flights