AirHint found the following cheapest return flights from Istanbul (IST) to Sao Paulo (GRU) in November 2025 (see full year).

Return flights

10 Nov - 18 Nov	KLM
09 Nov - 17 Nov	KLM
17 Nov - 25 Nov	KLM
10 Nov - 15 Nov	KLM
16 Nov - 27 Nov	KLM
14 Nov - 26 Nov	KLM
15 Nov - 30 Nov	KLM
12 Nov - 16 Nov	KLM
12 Nov - 19 Nov	KLM
07 Nov - 09 Nov	KLM
28 Nov - 07 Dec	KLM
25 Nov - 06 Dec	KLM
26 Nov - 06 Dec	KLM
25 Nov - 05 Dec	KLM
17 Nov - 11 Dec	KLM
25 Nov - 08 Dec	KLM
11 Nov - 05 Dec	KLM
24 Nov - 31 Dec	Air Europa
29 Nov - 19 Dec	British Airways
26 Nov - 06 Dec	Turkish Airlines	direct

Also check the deals for one-way flights from Istanbul to Sao Paulo in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Istanbul to Sao Paulo in November from 675€

Return flights