AirHint found the following cheapest return flights from Istanbul (IST) to Sao Paulo (GRU) in November 2025 (see full year).

Return flights

09 Nov - 21 Nov	Air Europa
12 Nov - 19 Nov	Air Europa
21 Nov - 28 Nov	Air Europa
12 Nov - 18 Nov	Air Europa
17 Nov - 28 Nov	Air Europa
12 Nov - 24 Nov	Air Europa
21 Nov - 25 Nov	Air Europa
20 Nov - 28 Nov	Lufthansa
09 Nov - 13 Nov	Air Europa
05 Nov - 27 Nov	Air Europa
19 Nov - 03 Dec	Royal Air Maroc
17 Nov - 17 Dec	Air Europa
14 Nov - 05 Dec	Air Europa
19 Nov - 03 Dec	Turkish Airlines	direct
17 Nov - 17 Dec	Turkish Airlines	direct
14 Nov - 05 Dec	Turkish Airlines	direct

Also check the deals for one-way flights from Istanbul to Sao Paulo in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Istanbul to Sao Paulo in November from 689€

Return flights