AirHint found the following cheapest return flights from Istanbul (IST) to Sao Paulo (GRU) in October 2025 (see full year).

Return flights

30 Oct - 06 Nov	Air Europa
09 Oct - 12 Oct	KLM
07 Oct - 14 Oct	KLM
06 Oct - 14 Oct	KLM
01 Oct - 07 Oct	KLM
03 Oct - 10 Oct	KLM
29 Oct - 06 Nov	Air Europa
30 Oct - 07 Nov	Air Europa
22 Oct - 21 Nov	Air Europa
01 Oct - 31 Oct	Air Europa
29 Oct - 02 Nov	Air Europa
29 Oct - 07 Nov	Air Europa
28 Oct - 12 Nov	Air Europa
15 Oct - 30 Oct	KLM
20 Oct - 27 Oct	Air Europa
01 Oct - 09 Oct	KLM
10 Oct - 17 Oct	KLM
16 Oct - 02 Nov	KLM
19 Oct - 02 Nov	Air Europa
17 Oct - 02 Nov	Air Europa

Also check the deals for one-way flights from Istanbul to Sao Paulo in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Istanbul to Sao Paulo in October from 748€

Return flights