AirHint found the following cheapest return flights from Istanbul (IST) to Sao Paulo (GRU) in October 2025 (see full year).

Return flights

08 Oct - 14 Oct	KLM
08 Oct - 21 Oct	KLM
08 Oct - 13 Oct	KLM
08 Oct - 11 Nov	KLM
08 Oct - 15 Oct	KLM
07 Oct - 11 Nov	Qatar Airways
10 Oct - 22 Oct	Qatar Airways
06 Oct - 03 Nov	KLM
13 Oct - 17 Oct	KLM
17 Oct - 29 Oct	KLM
14 Oct - 21 Oct	British Airways
05 Oct - 08 Nov	British Airways
20 Oct - 25 Oct	KLM
02 Oct - 13 Oct	British Airways
28 Oct - 02 Nov	Air Europa
18 Oct - 17 Nov	Air Europa
28 Oct - 02 Nov	Turkish Airlines	direct
06 Oct - 03 Nov	Turkish Airlines	direct
08 Oct - 11 Nov	Turkish Airlines	direct
07 Oct - 11 Nov	Turkish Airlines	direct

Also check the deals for one-way flights from Istanbul to Sao Paulo in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Sao Paulo

Cheap car rent in Sao Paulo

Cheapest return flights from Istanbul to Sao Paulo in October from 713€

Return flights