AirHint found the following cheapest return flights from Istanbul (IST) to Rome (FCO) in October 2026 (see full year).

Return flights

14 Oct - 18 Oct	AJet
16 Oct - 18 Oct	AJet
10 Oct - 17 Oct	AJet
19 Oct - 22 Oct	AJet
07 Oct - 10 Oct	AJet
03 Oct - 10 Oct	AJet
08 Oct - 11 Oct	AJet
10 Oct - 18 Oct	AJet
17 Oct - 24 Oct	AJet
06 Oct - 09 Oct	AJet
29 Oct - 05 Nov	Air Serbia
29 Oct - 05 Nov	Turkish Airlines	direct

Also check the deals for one-way flights from Istanbul to Rome in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Istanbul to Rome in October from 111€

Return flights